Complement receptor-3 negatively regulates the phagocytosis of degenerated myelin through tyrosine kinase Syk and cofilin
<p>Abstract</p> <p>Background</p> <p>Intact myelin, which normally surrounds axons, breaks down in Wallerian degeneration following axonal injury and during neurodegenerative diseases such as multiple sclerosis. Clearance of degenerated myelin by phagocytosis is essential since myelin impedes repair...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2012-07-01
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| Serier: | Journal of Neuroinflammation |
| Fag: | |
| Online adgang: | http://www.jneuroinflammation.com/content/9/1/166 |
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