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Pravastatin inhibits cell proliferation and increased MAT1A expression in hepatocarcinoma cells and in vivo models

<p>Abstract</p> <p>Background</p> <p>Statins may have therapeutic effects on hepatocarcinoma (HCC). This type of disorder is the most common malignant primary tumour in the liver. Our objective was to determine whether pravastatin had a therapeutic effect in vitro and in vivo models.</p> <p>Method</...

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Principais autores: Hijona Elizabeth, Banales Jesús, Hijona Lander, Medina Juan, Arenas Juan, Herreros-Villanueva Marta, Aldazabal Pablo, Bujanda Luis
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2012-02-01
Serier:Cancer Cell International
Fag:
Pravastatin
Sorafenib
Hepatocarcinoma
Statins
Online adgang:http://www.cancerci.com/content/12/1/5
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