Are zinc-bound metallothionein isoforms (I+II and III) involved in impaired thymulin production and thymic involution during ageing?

<p>Abstract</p> <p>Background</p> <p>With advancing age, thymic efficiency shows progressive decline due to thymic involution allowing impaired cell-mediated immunity and the appearance of age-related diseases. The intrinsic cause of thymic involution is still undefined. Chronic inflammation and hig...

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Bibliographic Details

Main Authors:	Cipriano Catia, Giacconi Robertina, Mocchegiani Eugenio, Muti Elisa, Gasparini Nazzarena, Malavolta Marco
Format:	Artigo
Language:	Inglês
Published:	BMC 2004-11-01
Series:	Immunity & Ageing
Subjects:	Thymic involution Metallothioneins IL-6 glucocorticoids zinc TECs inflammation ageing longevity
Online Access:	http://www.immunityageing.com/content/1/1/5
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