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Interleukin 15 (IL15)-based near-infrared photoimmunotherapy

Abstract Near-infrared photoimmunotherapy (NIR-PIT) is a highly selective cancer therapy based on a targeted monoclonal antibody conjugated to phthalocyanine-based photoabsorber, IRDye700DX (IR700). Following injection, near-infrared light activates the conjugate causing direct cytotoxicity and immu...

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Principais autores: Motofumi Suzuki, Aki Furusawa, Hiroshi Yamamoto, Makoto Kano, Miyu Kano, Seiichiro Takao, Shuhei Okuyama, Peter L. Choyke, Hisataka Kobayashi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2025-08-01
coleção:Cancer Immunology, Immunotherapy
Assuntos:
Interleukin-15
Immunogenic cell death
Near-infrared photoimmunotherapy
Tumor treatment
Acesso em linha:https://doi.org/10.1007/s00262-025-04151-8
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