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Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy

A detailed look at the properties of a novel USP30 inhibitor applied to studies of mitophagy and pexophagy. The deubiquitylase USP30 is an actionable target considered for treatment of conditions associated with defects in the PINK1-PRKN pathway leading to mitophagy. We provide a detailed cell biolo...

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Váldodahkkit: Emma V Rusilowicz-Jones, Francesco G Barone, Fernanda Martins Lopes, Elezabeth Stephen, Heather Mortiboys, Sylvie Urbé, Michael J Clague
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Life Science Alliance LLC 2022-02-01
Ráidu:Life Science Alliance
Liŋkkat:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202101287
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