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Alectinib: a novel second generation anaplastic lymphoma kinase (ALK) inhibitor for overcoming clinically-acquired resistance

The development of inhibitors for the tyrosine anaplastic lymphoma kinase (ALK) has advanced rapidly, driven by biology and medicinal chemistry. The first generation ALK inhibitor crizotinib was granted US FDA approval with only four years of preclinical and clinical testing. Although this drug offe...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Zilan Song, Meining Wang, Ao Zhang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2015-01-01
Rangatū:Acta Pharmaceutica Sinica B
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211383514001282
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