Inhibition of N-acetylglucosaminyltransferase V alleviates diabetic cardiomyopathy in mice by attenuating cardiac hypertrophy and fibrosis

Abstract Background The pathogenesis of diabetic cardiomyopathy is closely linked to abnormal glycosylation modifications. N-acetylglucosaminyltransferase V (GnT-V), which catalyzes the production of N-linked -1–6 branching of oligosaccharides, is involved in several pathophysiological mechanisms of...

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Detalhes bibliográficos

Principais autores:	Ran Zhao, Jianqiang Hu, He Wen, Jieqiong Zhao, Ying Wang, Xiaona Niu, Mingming Zhang, Tingting Wang, Yan Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-07-01
coleção:	Nutrition & Metabolism
Assuntos:	Diabetic cardiomyopathy GnT-V Integrinβ1 Hypertrophy Fibrosis
Acesso em linha:	https://doi.org/10.1186/s12986-024-00797-w
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