Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation[S]

Lysophosphatidic acid (LPA), a bioactive lysophospholipid, accumulates in the atherosclerotic plaque. It has the capacity to activate mast cells, which potentially exacerbates plaque progression. In this study, we thus aimed to investigate whether LPA contributes to plaque destabilization by modulat...

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Bibliografische Detailangaben

Hauptverfasser:	Martine Bot, Saskia C.A. de Jager, Luke MacAleese, H. Maxime Lagraauw, Theo J.C. van Berkel, Paul H.A. Quax, Johan Kuiper, Ron M.A. Heeren, Erik A.L. Biessen, Ilze Bot
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2013-05-01
Schriftenreihe:	Journal of Lipid Research
Schlagworte:	atherosclerosis plaque stability macrophage
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0022227520421650
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