CD4<sup>+ </sup>CD25<sup>+ </sup>FoxP3<sup>+ </sup>regulatory T cells suppress cytotoxicity of CD8<sup>+ </sup>effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenchymal level
<p>Abstract</p> <p>Background</p> <p>CD4<sup>+ </sup>CD25<sup>+ </sup>forkhead box P3 (FoxP3)<sup>+ </sup>regulatory T cells (T reg cells) are known to suppress adaptive immune responses, key control tolerance and autoimmunity.</p> <p>Methods</p> <p>We challenged the role of CD4<sup>+ </sup>T reg ce...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMC
2012-02-01
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| Edice: | Journal of Neuroinflammation |
| Témata: | |
| On-line přístup: | http://www.jneuroinflammation.com/content/9/1/41 |
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