Genomic and molecular characterisation of a KPC-producing Klebsiella pneumoniae clinical isolate resistant to meropenem-vaborbactam, imipenem-relebactam, and ceftazidime-avibactam

Abstract Background Resistance to carbapenems and third-generation cephalosporins is increasing in Klebsiella pneumoniae globally, restricting therapeutic options. The β-lactam/β-lactamase inhibitor combinations are widely used to circumvent β-lactamase-mediated resistance. In 2021, an unusual K. pn...

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Үндсэн зохиолчид:	Yu Wan, Joshua L. C. Wong, Julia Sanchez-Garrido, Wen Wen Low, Jane F. Turton, Fabio Morecchiato, Ilaria Baccani, Kirsty Dodgson, Gian Maria Rossolini, Neil Woodford, Gad Frankel, Elita Jauneikaite, Danièle Meunier, Katie L. Hopkins
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2026-05-01
Цуврал:	BMC Genomic Data
Нөхцлүүд:	Klebsiella pneumoniae Antimicrobial resistance Carbapenem resistance β-Lactamase inhibitors KPC-157 OmpK36
Онлайн хандалт:	https://doi.org/10.1186/s12863-026-01421-x
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!