Pharmacokinetics of post-transplant cyclophosphamide and its associations with clinical outcomes in pediatric haploidentical hematopoietic stem cell transplantation

Abstract Background Post-transplantation cyclophosphamide (PTCy) has paved the way for the increased use of alternative donors, including haploidentical familial donors, with acceptable engraftment and graft-versus-host disease (GVHD) rates. However, pharmacokinetic studies of PTCy in the pediatric...

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Autores principales:	Kyung Taek Hong, Sungyeun Bae, Yoon Sunwoo, Juyeon Lee, Hyun Jin Park, Bo Kyung Kim, Jung Yoon Choi, Joo-Youn Cho, Kyung-Sang Yu, Jaeseong Oh, Hyoung Jin Kang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-03-01
Colección:	Biomarker Research
Materias:	Haploidentical stem cell transplants Cyclophosphamide Pediatrics Pharmacokinetics Clinical outcomes
Acceso en línea:	https://doi.org/10.1186/s40364-025-00749-3
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