Acute leukoencephalopathy associated with daratumumab treatment in POEMS syndrome: a case report

ObjectivesDaratumumab, a monoclonal antibody against CD38, is increasingly used in the treatment of multiple myeloma, other hematological malignancies and autoimmune diseases. Little is known about its CNS toxicity. We present a case of a patient with POEMS syndrome (syndrome of polyneuropathy, orga...

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Main Authors:	Lukas Steinegger, Nathalie Nierobisch, Anthony De Vere-Tyndall, Bettina Schreiner, Patrick Roth, Ludwig Kappos, Veronika Kana, Marina Herwerth
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2024-09-01
Series:	Frontiers in Immunology
Subjects:	POEMS daratumumab rapidly progressive leukoencephalopathy CD38-antibody toxic leukoencephalopathy
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1451693/full
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