Direct and indirect effects of spliceosome disruption compromise gene regulation by nonsense-mediated mRNA decay
Pre-mRNA splicing, carried out in the nucleus by a large ribonucleoprotein machine known as the spliceosome, is functionally and physically coupled to the mRNA surveillance pathway in the cytoplasm called nonsense-mediated mRNA decay (NMD). The NMD pathway monitors for premature translation terminat...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis Group
2025-12-01
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| Serier: | RNA Biology |
| Fag: | |
| Online adgang: | https://www.tandfonline.com/doi/10.1080/15476286.2025.2552517 |
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