Exploration of protective strategies against oligodendrocyte cell death in Krabbe disease models
Krabbe disease (KD) patients accumulate psychosine (galactosylsphingosine), a cytotoxic metabolite for oligodendrocytes, inducing early demyelination. Apoptosis has been suggested that plays an important role in psychosine-induced oligodendrocytes cell death in culture and in brains of Krabbe patien...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2015-02-01
|
| Schriftenreihe: | Frontiers in Cellular Neuroscience |
| Schlagworte: | |
| Online-Zugang: | http://journal.frontiersin.org/Journal/10.3389/conf.fncel.2015.35.00034/full |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|