Single-cell transcriptome analysis uncovers underlying mechanisms of acute liver injury induced by tripterygium glycosides tablet in mice

Tripterygium glycosides tablet (TGT), the classical commercial drug of Tripterygium wilfordii Hook. F. has been effectively used in the treatment of rheumatoid arthritis, nephrotic syndrome, leprosy, Behcet's syndrome, leprosy reaction and autoimmune hepatitis. However, due to its narrow and limited...

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Autori principali:	Qiuyan Guo, Jiangpeng Wu, Qixin Wang, Yuwen Huang, Lin Chen, Jie Gong, Maobo Du, Guangqing Cheng, Tianming Lu, Minghong Zhao, Yuan Zhao, Chong Qiu, Fei Xia, Junzhe Zhang, Jiayun Chen, Feng Qiu, Jigang Wang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2023-08-01
Serie:	Journal of Pharmaceutical Analysis
Soggetti:	Tripterygium glycosides tablet Acute liver injury scRNA-seq
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2095177923000412
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