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Steps of actin filament branch formation by Arp2/3 complex investigated with coarse-grained molecular dynamics

The nucleation of actin filament branches by the Arp2/3 complex involves activation through nucleation promotion factors (NPFs), recruitment of actin monomers, and binding of the complex to the side of actin filaments. Because of the large system size and processes that involve flexible regions and...

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Autori principali: Shuting Zhang, Dimitrios Vavylonis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2023-01-01
Serie:Frontiers in Cell and Developmental Biology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fcell.2023.1071977/full
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