Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression

DBC1 has been characterized as a key regulator of physiological and pathophysiological activities, such as DNA damage, senescence, and tumorigenesis. However, the mechanism by which the functional stability of DBC1 is regulated has yet to be elucidated. Here, we report that the ubiquitination-mediat...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Qiangqiang Liu, Qian Luo, Jianyu Feng, Yanping Zhao, Biao Ma, Hongcheng Cheng, Tian Zhao, Hong Lei, Chenglong Mu, Linbo Chen, Yuanyuan Meng, Jiaojiao Zhang, Yijia Long, Jingyi Su, Guo Chen, Yanjun Li, Gang Hu, Xudong Liao, Quan Chen, Yushan Zhu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2022-08-01
Edice:	eLife
Témata:	DBC1 ubiquitination SIAH2 hypoxia OTUD5
On-line přístup:	https://elifesciences.org/articles/81247
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!