High glucose enhances the activation of NLRP3 inflammasome by ambient fine particulate matter in alveolar macrophages

Abstract Background Epidemiological studies have demonstrated that individuals with preexisting conditions, including diabetes mellitus (DM), are more susceptible to air pollution. However, the underlying mechanisms remain unclear. In this study, we proposed that a high glucose setting enhances ambi...

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Главные авторы:	Yiqun Mo, Luke Mo, Yue Zhang, Yuanbao Zhang, Jiali Yuan, Qunwei Zhang
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2023-11-01
Серии:	Particle and Fibre Toxicology
Предметы:	Ambient fine particulate matter (PM2.5) Alveolar macrophage High glucose NLRP3 inflammasome IL-1β MMP-9
Online-ссылка:	https://doi.org/10.1186/s12989-023-00552-8
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