Antiparasitic effect of synthetic aromathecins on Leishmania infantum

Abstract Background Canine leishmaniasis is a zoonotic disease caused by Leishmania infantum, being the dogs one of the major reservoirs of human visceral leishmaniasis. DNA topology is a consolidated target for drug discovery. In this regard, topoisomerase IB – one of the enzymes controlling DNA to...

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Bibliografiske detaljer

Principais autores:	Rosa M. Reguera, Raquel Álvarez-Velilla, Bárbara Domínguez-Asenjo, Camino Gutiérrez-Corbo, Rafael Balaña-Fouce, Mark Cushman, Yolanda Pérez-Pertejo
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2019-11-01
Serier:	BMC Veterinary Research
Fag:	Leishmania DNA-topoisomerase IB Camptothecin Aromathecins
Online adgang:	http://link.springer.com/article/10.1186/s12917-019-2153-9
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