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Clinicopathological and genetic study of a rare occurrence: Malignant transformation of fibrous dysplasia of the jaws

Abstract Background Malignant transformation of fibrous dysplasia (FD) is very rare and little is known about this occurrence. Methods We present the detailed clinical course of three cases of osteosarcoma arising from FD of the jaws and explore the genetic aberrations by Sanger sequencing, whole‐ex...

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Principais autores: Ruirui Shi, Xuefen Li, Jianyun Zhang, Feng Chen, Ming Ma, Yanrui Feng, Tiejun Li
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2022-01-01
coleção:Molecular Genetics & Genomic Medicine
Assuntos:
copy number alterations
fibrous dysplasia
GNAS
malignant transformation
TP53
Acesso em linha:https://doi.org/10.1002/mgg3.1861
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