Evolution of Yin and Yang isoforms of a chromatin remodeling subunit precedes the creation of two genes

Genes can encode multiple isoforms, broadening their functions and providing a molecular substrate to evolve phenotypic diversity. Evolution of isoform function is a potential route to adapt to new environments. Here we show that de novo, beneficial alleles in the nurf-1 gene became fixed in two lab...

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Detalhes bibliográficos

Principais autores:	Wen Xu, Lijiang Long, Yuehui Zhao, Lewis Stevens, Irene Felipe, Javier Munoz, Ronald E Ellis, Patrick T McGrath
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2019-09-01
coleção:	eLife
Assuntos:	other Caenorhabditis species Isoform evolution adaptive conflict alternative transcripts chromatin remodeling
Acesso em linha:	https://elifesciences.org/articles/48119
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