Small-diameter artery grafts engineered from pluripotent stem cells maintain 100% patency in an allogeneic rhesus macaque model

Summary: Autologous vascular grafts, the only clinically approved option for small-diameter (<6 mm) revascularizations, require invasive harvesting and have limited availability and variable quality. To address these challenges, we develop a 3-mm-diameter artery graft by using arterial endothelial c...

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Hauptverfasser:	Jue Zhang, Diana Marcela Tabima, David Vereide, Weifeng Zeng, Nicholas J. Albano, Sarah Lyon, Peter J. Nicksic, Ellen C. Shaffrey, Robert E. George, Mitchell D. Probasco, Elizabeth S. Perrin, Yiyang Xu, Matthew E. Brown, Ron Stewart, Naomi C. Chesler, Lih-Sheng Turng, Samuel O. Poore, Igor I. Slukvin, James A. Thomson, John P. Maufort
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-03-01
Schriftenreihe:	Cell Reports Medicine
Schlagworte:	pluripotent stem cells endothelial cells ePTFE vascular grafts vascular disease peripheral bypass rhesus macaque
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2666379125000758
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