Synthesis of C3-symmetric star-shaped molecules containing α-amino acids and dipeptides via Negishi coupling as a key step

We demonstrate a new synthetic strategy toward star-shaped C3-symmetric molecules containing α-amino acid (AAA) derivatives and dipeptides. In this regard, trimerization and Negishi cross-coupling reactions are used as the key steps starting from readily available 4’-iodoacetophenone and L-serine. T...

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Hlavní autoři:	Sambasivarao Kotha, Saidulu Todeti
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Beilstein-Institut 2019-02-01
Edice:	Beilstein Journal of Organic Chemistry
Témata:	amino acids cyclotrimerization Negishi coupling peptide
On-line přístup:	https://doi.org/10.3762/bjoc.15.33
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