Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation

The current paradigm of pancreatic neoplastic transformation proposes an initial step whereby acinar cells convert into acinar-to-ductal metaplasias, followed by progression of these lesions into neoplasias under sustained oncogenic activity and inflammation. Understanding the molecular mechanisms d...

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Bibliografiske detaljer

Principais autores:	Yiannis Drosos, Geoffrey Neale, Jianming Ye, Leena Paul, Emin Kuliyev, Anirban Maitra, Anna L Means, M Kay Washington, Jerold Rehg, David B Finkelstein, Beatriz Sosa-Pineda
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2016-03-01
Serier:	Neoplasia: An International Journal for Oncology Research
Online adgang:	http://www.sciencedirect.com/science/article/pii/S1476558616000221
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