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HDAC1 dysregulation promotes pro-inflammatory microglial activation and aggravates post-stroke neuroinflammation

Background Histone deacetylase 1 (HDAC1) is a key epigenetic regulator involved in DNA repair and neuronal survival. While HDAC1 downregulation has been implicated in ischemic brain injury, its role in regulating microglial functional shift and neuroinflammation remains unclear. This study aimed to...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Jui-Shen Chen, Hao-Kuang Wang, Yu-Ting Su, Yu-Cheng Ho, Cheng-Loong Liang, Yung-Kuo Lee, Tian-Huei Chu, Yun-Shin Lin, Cheng-Chun Wu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis Group 2025-12-01
Schriftenreihe:Annals of Medicine
Schlagworte:
Online-Zugang:https://www.tandfonline.com/doi/10.1080/07853890.2025.2597624
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