Association of BDNF and MMP-9 single-nucleotide polymorphisms with the clinical phenotype of schizophrenia

ObjectiveSchizophrenia is a highly polygenic psychiatric disorder; however, the complex genetic architecture underlying the pathogenesis remains elusive. Brain-derived neurotrophic factor (BDNF), a neurotrophin, and matrix metalloproteinase 9 (MMP-9), a gelatinase B, are the promising candidate gene...

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Hlavní autoři:	Lihong Pan, Zhonghai Cao, Lianghu Chen, Min Qian, Yuzhong Yan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-10-01
Edice:	Frontiers in Psychiatry
Témata:	schizophrenia BDNF MMP-9 single-nucleotide polymorphisms clinical phenotype
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fpsyt.2022.941973/full
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