Enhanced meningeal lymphatic drainage ameliorates lipopolysaccharide-induced brain injury in aged mice

Abstract Background Sepsis-associated encephalopathy (SAE) is an acute cerebral dysfunction caused by sepsis. Neuroinflammation induced by sepsis is considered a potential mechanism of SAE; however, very little is known about the role of the meningeal lymphatic system in SAE. Methods Sepsis was esta...

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Principais autores:	Hongquan Dong, Xiaonan Dai, Yin Zhou, Chonglong Shi, Piplu Bhuiyan, Zhaochu Sun, Nana Li, Wenjie Jin
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2024-01-01
סדרה:	Journal of Neuroinflammation
נושאים:	Sepsis-associated encephalopathy Meningeal lymphatics Lymphatic endothelial cells VEGF-C Neuroinflammation
גישה מקוונת:	https://doi.org/10.1186/s12974-024-03028-4
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