Targeting entry into mitochondria for increased anticancer efficacy of BCL-XL-selective inhibitors in lung cancer

The BCL-XL-selective inhibitors exhibit potential clinical application value when combined with chemotherapeutic drugs for the treatment of solid tumors. However, their efficacy in these settings is still low when treated with BCL-XL inhibitors alone in solid tumors. The mechanism responsible for th...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Liangping Li, Pingping Li, Huanhuan Song, Xuesong Ma, Shulan Zeng, Yan Peng, Guohai Zhang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2022-03-01
Цуврал:	Pharmacological Research
Нөхцлүүд:	BCL-XL-selective inhibitor Off-target Improve On-target Synergistic therapy
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S1043661822000408
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!