Importance of Crosstalk Between Chronic Lymphocytic Leukemia Cells and the Stromal Microenvironment: Direct Contact, Soluble Factors, and Extracellular Vesicles

Chronic lymphocytic leukemia (CLL) is caused by the accumulation of malignant B cells due to a defect in apoptosis and the presence of small population of proliferating cells principally in the lymph nodes. The abnormal survival of CLL B cells is explained by a plethora of supportive stimuli produce...

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Principais autores:	Nathan Dubois, Emerence Crompot, Nathalie Meuleman, Dominique Bron, Laurence Lagneaux, Basile Stamatopoulos
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2020-08-01
סדרה:	Frontiers in Oncology
נושאים:	chronic lymphocytic leukemia microenvironment mesenchymal stromal cells extracellular vesicles prognostic factor
גישה מקוונת:	https://www.frontiersin.org/article/10.3389/fonc.2020.01422/full
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