Sphingosine kinase-1 is required for toll mediated beta-defensin 2 induction in human oral keratinocytes.

<h4>Background</h4>Host defense against invading pathogens is triggered by various receptors including toll-like receptors (TLRs). Activation of TLRs is a pivotal step in the initiation of innate, inflammatory, and antimicrobial defense mechanisms. Human beta-defensin 2 (HBD-2) is a cationic antimic...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Manjunatha R Benakanakere, Jiawei Zhao, Johnah C Galicia, Michael Martin, Denis F Kinane
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2010-07-01
Serija:	PLoS ONE
Online dostop:	https://doi.org/10.1371/journal.pone.0011512
Oznake:	Označite Brez oznak, prvi označite!