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Microglial STING is a central safeguard against neurological decline with age

Summary: Functional decline of the central nervous system (CNS) is driven by the breakdown of the blood-brain barrier (BBB) and attendant inflammation, all hallmarks of age-related neurodegeneration. Despite intense interest in how the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (S...

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Guardado en:
Autores principales: Katherine B. Sulka, Kimberly A. Carroll, Machlan Sawden, Jacob W. Hopkins, Sasha A. Smolgovsky, Abraham L. Bayer, Eric Reed, Albert Tai, Pilar Alcaide, Philip Haydon, Shruti Sharma
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2025-06-01
Colección:Cell Reports
Materias:
CP: Immunology
CP: Neuroscience
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2211124725005200
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