AGE induced macrophage-derived exosomes induce endothelial dysfunction in diabetes via miR-22-5p/FOXP1

Abstract Background Endothelial dysfunction is a pivotal contributor to cardiovascular complications in individuals with diabetes. However, the precise role of macrophages and their exosomes in the diabetic milieu remains elusive. Methods Exosomes (Exos) were isolated from the supernatants of macrop...

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Detalles Bibliográficos

Principais autores:	Yang Ji, Huanzhen Chen, Lihua Pang, Changnong Chen, Sha Wang, Jing Chen, Lei Fang, Benrong Liu, Yongruo Cheng, Shiming Liu, Yun Zhong
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-04-01
Series:	Cardiovascular Diabetology
Assuntos:	Endotheliocytes Macrophage Exosomes microRNAs Diabetes Inflammation
Acceso en liña:	https://doi.org/10.1186/s12933-025-02715-7
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