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Identification of CLEC10A as a human lectin for pancreatic ductal adenocarcinoma

Abstract The mechanism by which glycans in pancreatic ductal adenocarcinoma (PDAC) interact with human endogenous lectins in the tumor microenvironment remains largely unknown. This study aimed to identify endogenous lectins that recognize and bind to pancreatic ductal adenocarcinomas. The reactivit...

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Principais autores: Shuntaro Tsukamoto, Hiroaki Tateno, Osamu Shimomura, Kana Yamamoto, Sayoko Saito, Jinko Murakami, Hiromitsu Nakahashi, Yoshihiro Miyazaki, Tsuyoshi Enomoto, Tatsuya Oda
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2025-05-01
סדרה:Scientific Reports
נושאים:
CLEC10A protein
Endogenous lectin
Pancreatic cancer
Tumor microenvironment
גישה מקוונת:https://doi.org/10.1038/s41598-025-02404-1
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