PRPF19 mediates the proteasomal degradation of VDR to exacerbate ferroptosis in diabetic nephropathy
Abstract Ferroptosis, an iron-dependent form of programmed cell death, is closely associated with tubular damage in diabetic nephropathy (DN). Glutathione peroxidase 4 (GPX4) is an important anti-oxidant enzyme, and plays a crucial role in protecting against ferroptosis. However, the regulatory mech...
I tiakina i:
| Ngā kaituhi matua: | , , , , , , , , , |
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| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
BMC
2025-05-01
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| Rangatū: | Cell Communication and Signaling |
| Ngā marau: | |
| Urunga tuihono: | https://doi.org/10.1186/s12964-025-02253-5 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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