BMPR2 affects valve development via ECM–receptor interaction in zebrafish

Abnormal cardiac valve development may lead to functional impairment in adulthood. BMPR2, a highly conserved receptor of the BMP family, exists in two subtypes (bmpr2a and bmpr2b) in zebrafish. However, the roles of bmpr2a and bmpr2b in valve development remain unclear. In this study, we generated t...

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Κύριοι συγγραφείς:	Yan Shi, Yanli Huang, Yu Xia, Yongqing Li, Yuequn Wang, Wuzhou Yuan, Fang Li, Zhigang Jiang, Yu Chen, Ping Zhu, Jian Zhuang, Xiushan Wu, Xiongwei Fan
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2026-03-01
Σειρά:	Frontiers in Cell and Developmental Biology
Θέματα:	bmpr2a bmpr2b ECM–receptor interaction mutant zebrafish valve development
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fcell.2026.1652622/full
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