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Concomitant BCR-ABL1 positive chronic myelogenous leukemia emerging in a patient with MPL W515L associated primary myelofibrosis

Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders characterized by proliferation of one or more cell lineages in the bone marrow. At present, the main criterion in the 2008 World Health Organization classification of MPNs is the presence of an underlying genetic abnorm...

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Principais autores: Juan C. Gomez-Gelvez, MD, Elena Ivan, MD, Bryan L. Betz, PhD, Megan S. Lim, MD, PhD
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2016-03-01
Serier:Human Pathology: Case Reports
Fag:
Myeloproliferative neoplasms
Chronic myelogenous leukemia
Primary myelofibrosis
BCR-ABL1
MPL W515L
Online adgang:http://www.sciencedirect.com/science/article/pii/S2214330015300419
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