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481 Interactions between buprenorphine and norbuprenorphine in neonatal opioid withdrawal syndrome

OBJECTIVES/GOALS: Buprenorphine (BUP) is used for opioid use disorder during pregnancy but causes neonatal opioid withdrawal syndrome (NOWS). The goal of this study was to determine the contribution of the active metabolite, norbuprenorphine (NorBUP), to the development of NOWS when the parent drug,...

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Autori principali: Julia Tobacyk, Brian J. Parks, Lori Coward, Michael D. Berquist, Gregory S. Gorman, Lisa K. Brents
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cambridge University Press 2023-04-01
Serie:Journal of Clinical and Translational Science
Accesso online:https://www.cambridge.org/core/product/identifier/S2059866123004946/type/journal_article
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