Sex-specific transcriptional signatures of oxycodone persist during withdrawal and abstinence in the suprachiasmatic nucleus of heterogeneous stock rats

Opioid use disorder (OUD) is a major public health problem. Sleep and circadian disruptions are recognized as hallmarks of substance use disorders, often emerging during withdrawal and lasting into abstinence. Little is known about the impact of opioids on the brain’s primary circadian pacemaker, th...

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Bibliografske podrobnosti

Principais autores:	Tara C. Delorme, Snehal Sambare, Benjamin R. Williams, Mackenzie C. Gamble, Lieselot L.G. Carrette, Leah C Solberg Woods, Lisa Maturin, Abraham A. Palmer, Olivier George, Ryan W. Logan
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2025-12-01
Serija:	Addiction Neuroscience
Teme:	Opioid use disorder Circadian rhythms Suprachiasmatic nucleus RNA sequencing Sex differences Heterogeneous stock rats
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2772392525000458
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