Real-world immune dynamics following COVID-19 vaccination and breakthrough infection: a paired-sample study in Zhejiang Province, China

IntroductionAs SARS-CoV-2 variants continue to spread, breakthrough infections (BTI) provide real-world insights into the durability and heterogeneity of COVID-19 vaccine-induced immunity. This study aimed to characterize the immune response dynamics and reconstruction characteristics after BTI in p...

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Autori principali:	Yuxin Hu, Youhong Weng, Xiaodong Li, Yihua Huang, Jinren Pan, Yahan Wu, Rongxian Liao, Ruoyao Gong, Longyou Zhao, Dingmei Zhang, Mengke Han, Yu Xu, Xiaoliang Zheng, Shaohong Lu, Qingming Kong, Enfu Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-03-01
Serie:	Frontiers in Immunology
Soggetti:	breakthrough infection COVID-19 hybrid immunity immune heterogeneity lower-quartile immune response
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1801564/full
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