PTP4A3 contributes to pathological retinal neovascularization and vascular leakage partly through the PI3K-AKT signalling pathway

Abstract Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus and an important cause of acquired blindness among working-age populations globally. Endothelial cell dysfunction is involved in the elevated diabetic retinal vascular leakage and pathological neovasculari...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Yong-kun Gui, Zhi-xin Yan, Rui-fang Ren, Rui-rui Zhu, De-wei Zhu, Yu-ying Sun, Ping Zhang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2026-03-01
Schriftenreihe:	Scientific Reports
Schlagworte:	PTP4A3 Vascular leakage Pathological neovascularization Diabetic retinopathy PI3K/AKT
Online-Zugang:	https://doi.org/10.1038/s41598-026-44537-x
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