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Epigenome-wide association study of asthma and wheeze in childhood and adolescence

Abstract Background Asthma heritability has only been partially explained by genetic variants and is known to be sensitive to environmental factors, implicating epigenetic modifications such as DNA methylation in its pathogenesis. Methods Using data collected in the Avon Longitudinal Study of Parent...

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Tallennettuna:
Päätekijät: Ryan Arathimos, Matthew Suderman, Gemma C. Sharp, Kimberley Burrows, Raquel Granell, Kate Tilling, Tom R. Gaunt, John Henderson, Susan Ring, Rebecca C. Richmond, Caroline L. Relton
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2017-10-01
Sarja:Clinical Epigenetics
Aiheet:
ALSPAC
Asthma
Wheeze
DNA methylation
Longitudinal
Mendelian randomization
Linkit:http://link.springer.com/article/10.1186/s13148-017-0414-7
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