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ARHGAP44-mediated regulation of the p53/C-myc/Cyclin D1 pathway in modulating the malignant biological behavior of osteosarcoma cells

Abstract Objective Osteosarcoma is a rare primary malignant tumor of the bone characterized by poor survival rates, owing to its unclear pathogenesis. Rho GTPase-activating protein 44 (ARHGAP44), which belongs to the Rho GTPase-activating protein family, has promising applications in the targeted th...

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Hlavní autoři: Shizhe Li, Jiancheng Xue, He Zhang, Guanning Shang
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2023-11-01
Edice:Journal of Orthopaedic Surgery and Research
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On-line přístup:https://doi.org/10.1186/s13018-023-04406-z
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