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Dysfunctional purinergic signaling correlates with disease severity in COVID-19 patients

Ectonucleotidases modulate inflammatory responses by balancing extracellular ATP and adenosine (ADO) and might be involved in COVID-19 immunopathogenesis. Here, we explored the contribution of extracellular nucleotide metabolism to COVID-19 severity in mild and severe cases of the disease. We verifi...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Anna Julia Pietrobon, Roberta Andrejew, Ricardo Wesley Alberca Custódio, Luana de Mendonça Oliveira, Juliete Nathali Scholl, Franciane Mouradian Emidio Teixeira, Cyro Alves de Brito, Talita Glaser, Julia Kazmierski, Christine Goffinet, Anna Claudia Turdo, Tatiana Yendo, Valeria Aoki, Fabricio Figueiró, Ana Maria Battastini, Henning Ulrich, Gill Benard, Alberto Jose da Silva Duarte, Maria Notomi Sato
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2022-09-01
Rangatū:Frontiers in Immunology
Ngā marau:
adenosine
ATP
CD39
CD73
COVID-19
SARS-CoV-2
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1012027/full
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