A New Pipeline for the Normalization and Pooling of Metabolomics Data

Pooling metabolomics data across studies is often desirable to increase the statistical power of the analysis. However, this can raise methodological challenges as several preanalytical and analytical factors could introduce differences in measured concentrations and variability between datasets. Sp...

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Hlavní autoři:	Vivian Viallon, Mathilde His, Sabina Rinaldi, Marie Breeur, Audrey Gicquiau, Bertrand Hemon, Kim Overvad, Anne Tjønneland, Agnetha Linn Rostgaard-Hansen, Joseph A. Rothwell, Lucie Lecuyer, Gianluca Severi, Rudolf Kaaks, Theron Johnson, Matthias B. Schulze, Domenico Palli, Claudia Agnoli, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, W. M. Monique Verschuren, Peter Engelfriet, Charlotte Onland-Moret, Roel Vermeulen, Therese Haugdahl Nøst, Ilona Urbarova, Raul Zamora-Ros, Miguel Rodriguez-Barranco, Pilar Amiano, José Maria Huerta, Eva Ardanaz, Olle Melander, Filip Ottoson, Linda Vidman, Matilda Rentoft, Julie A. Schmidt, Ruth C. Travis, Elisabete Weiderpass, Mattias Johansson, Laure Dossus, Mazda Jenab, Marc J. Gunter, Justo Lorenzo Bermejo, Dominique Scherer, Reza M. Salek, Pekka Keski-Rahkonen, Pietro Ferrari
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-09-01
Edice:	Metabolites
Témata:	cancer epidemiology normalization pooling technical variability metabolomics metabolites
On-line přístup:	https://www.mdpi.com/2218-1989/11/9/631
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