Mechanism of Lethal Toxin Neutralization by a Human Monoclonal Antibody Specific for the PA20 Region of Bacillus anthracis Protective Antigen

The primary immunogenic component of the currently approved anthrax vaccine is the protective antigen (PA) unit of the binary toxin system. PA-specific antibodies neutralize anthrax toxins and protect against infection. Recent research has determined that in humans, only antibodies specific for part...

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Bibliografische gegevens

Hoofdauteurs:	Jessica Camacho, Jianhui Zhou, Jinying Sun, Donald Reason, Justine Liberato
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2011-08-01
Reeks:	Toxins
Onderwerpen:	anthrax Bacillus anthracis antibody epitope paratope human monoclonal antibody protective antigen furin toxin neutralization
Online toegang:	http://www.mdpi.com/2072-6651/3/8/979/
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