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A Pralidoxime Nanocomplex Formulation Targeting Transferrin Receptors for Reactivation of Brain Acetylcholinesterase After Exposure of Mice to an Anticholinesterase Organophosphate

Kathleen F Pirollo,1 Manish Moghe,1 Miaoyin Guan,1 Antonina S Rait,1 Aibing Wang,1 Sang-Soo Kim,1,2 Esther H Chang,1 Joe B Harford2 1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, 20057, USA; 2SynerGene Therapeutics, Inc., Potomac,...

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Hoofdauteurs: Pirollo KF, Moghe M, Guan M, Rait AS, Wang A, Kim SS, Chang EH, Harford JB
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2024-01-01
Reeks:International Journal of Nanomedicine
Onderwerpen:
lipid nanoparticle
nanodelivery
organophosphate
paraoxon
blood-brain barrier
transcytosis
Online toegang:https://www.dovepress.com/a-pralidoxime-nanocomplex-formulation-targeting-transferrin-receptors--peer-reviewed-fulltext-article-IJN
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