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Restoring mortality data in the FOURIER cardiovascular outcomes trial of evolocumab in patients with cardiovascular disease: a reanalysis based on regulatory data

Objective The FOURIER trial showed a benefit of the PCSK9 inhibitor evolocumab over placebo with respect to cardiovascular outcomes in patients with cardiovascular disease. However, we observed some inconsistencies between the information in the Clinical Study Report (CSR) and that in the 2017 prima...

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Hlavní autoři: Ken Bassett, James Wright, Leire Leache, Luis Carlos Saiz, Juan Erviti, Thomas L Perry, Mohamed Ben-Eltriki, Ciprian Jauca, Marta Gutiérrez-Valencia
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2022-12-01
Edice:BMJ Open
On-line přístup:https://bmjopen.bmj.com/content/12/12/e060172.full
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