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Mechanosensitive TRPV4 Channel-Induced Extracellular ATP Accumulation at the Acupoint Mediates Acupuncture Analgesia of Ankle Arthritis in Rats

(1) Background: Acupuncture (AP) is a safe and effective analgesic therapy. Understanding how fine needles trigger biological signals can help us optimize needling manipulation to improve its efficiency. Adenosine accumulation in treated acupoints is a vital related event. Here, we hypothesized that...

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Principais autores: Yawen Zheng, Weimin Zuo, Dan Shen, Kaiyu Cui, Meng Huang, Di Zhang, Xueyong Shen, Lina Wang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2021-05-01
coleção:Life
Assuntos:
acupuncture analgesia
mechano-sensitivity
TRPV4
extracellular ATP
nucleotidases
Acesso em linha:https://www.mdpi.com/2075-1729/11/6/513
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