Inflammasome Activation Induced by Perfringolysin O of Clostridium perfringens and Its Involvement in the Progression of Gas Gangrene

Clostridium perfringens (C. perfringens) is Gram-positive anaerobic, spore-forming rod-shaped bacterial pathogen that is widely distributed in nature. This bacterium is known as the causative agent of a foodborne illness and of gas gangrene. While the major virulence factors are the α-toxin and perf...

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Автори:	Kiyonobu Yamamura, Hiroshi Ashida, Tokuju Okano, Ryo Kinoshita-Daitoku, Shiho Suzuki, Kaori Ohtani, Miwako Hamagaki, Tohru Ikeda, Toshihiko Suzuki
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2019-10-01
Серія:	Frontiers in Microbiology
Предмети:	Clostridium perfringens gas gangrene inflammasome caspase-1 perfringolysin O
Онлайн доступ:	https://www.frontiersin.org/article/10.3389/fmicb.2019.02406/full
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