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Chondroitin sulfate proteoglycan CSPG4 as a novel hypoxia-sensitive marker in pancreatic tumors.

CSPG4 marks pericytes, undifferentiated precursors and tumor cells. We assessed whether the shed ectodomain of CSPG4 (sCSPG4) might circulate and reflect potential changes in CSPG4 tissue expression (pCSPG4) due to desmoplastic and malignant aberrations occurring in pancreatic tumors. Serum sCSPG4 w...

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Principais autores: Shereen Keleg, Alexandr Titov, Anette Heller, Thomas Giese, Christine Tjaden, Sufian S Ahmad, Matthias M Gaida, Andrea S Bauer, Jens Werner, Nathalia A Giese
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Acceso en liña:https://doi.org/10.1371/journal.pone.0100178
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